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Design of novel proliposome formulation for antioxidant peptide, glutathione with enhanced oral bioavailability and stability

To develop proliposome formulations to improve the oral bioavailability of l-glutathione (GSH), GSH-loaded proliposomes were prepared using the granule method. Mannitol was selected as an effective excipient to achieve the desired particle size, entrapment efficiency (EE), and solubility for oral de...

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Detalhes bibliográficos
Publicado no:Drug Deliv
Main Authors: Byeon, Jong Chan, Lee, Sang-Eun, Kim, Tae-Hyeon, Ahn, Jung Bin, Kim, Dong-Hyun, Choi, Jin-Seok, Park, Jeong-Sook
Formato: Artigo
Idioma:Inglês
Publicado em: Taylor & Francis 2019
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6407602/
https://ncbi.nlm.nih.gov/pubmed/30843439
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1080/10717544.2018.1551441
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