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ACAT: A Fast and Powerful p Value Combination Method for Rare-Variant Analysis in Sequencing Studies
Set-based analysis that jointly tests the association of variants in a group has emerged as a popular tool for analyzing rare and low-frequency variants in sequencing studies. The existing set-based tests can suffer significant power loss when only a small proportion of variants are causal, and thei...
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| 出版年: | Am J Hum Genet |
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| 主要な著者: | , , , , , |
| フォーマット: | Artigo |
| 言語: | Inglês |
| 出版事項: |
Elsevier
2019
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| 主題: | |
| オンライン･アクセス: | https://ncbi.nlm.nih.gov/pmc/articles/PMC6407498/ https://ncbi.nlm.nih.gov/pubmed/30849328 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.ajhg.2019.01.002 |
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