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Automodified Poly(ADP-Ribose) Polymerase Analysisto Monitor DNA Damagein Peripheral Lymphocytes of Floriculturists Occupationally Exposed to Pesticides

Increased DNA damage and the propension to cancer development, depend on the modulation of the mechanisms to control and maintain genomic integrity. Poly(ADP-Ribose)Polymerase activation and automodification are early responses to genotoxic stress. Upon binding to DNA strand breaks, the enzyme, a mo...

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Detalhes bibliográficos
Publicado no:Cells
Main Authors: Imperato, Serena, Mistretta, Carmela, Marone, Maria, Migliaccio, Ilaria, Pulcinelli, Ilaria, Faraone Mennella, Maria Rosaria
Formato: Artigo
Idioma:Inglês
Publicado em: MDPI 2019
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6407306/
https://ncbi.nlm.nih.gov/pubmed/30744056
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3390/cells8020137
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