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Characterization of SIRT1/DNMTs Functions and LINE-1 Methylation in Patients with Age-Related Macular Degeneration

Previous studies proposed the application of DNA methylation signatures as clinical biomarkers of age-related macular degeneration (AMD). However, the characterization of Long Interspersed Nuclear Element-1 (LINE-1) methylation levels—a surrogate marker of global DNA methylation—in AMD patients has...

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Detalhes bibliográficos
Publicado no:J Clin Med
Main Authors: Maugeri, Andrea, Barchitta, Martina, Fallico, Matteo, Castellino, Niccolò, Reibaldi, Michele, Agodi, Antonella
Formato: Artigo
Idioma:Inglês
Publicado em: MDPI 2019
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6406755/
https://ncbi.nlm.nih.gov/pubmed/30717113
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3390/jcm8020159
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