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Gli Proteins: Regulation in Development and Cancer

Gli proteins are transcriptional effectors of the Hedgehog signaling pathway. They play key roles in the development of many organs and tissues, and are deregulated in birth defects and cancer. We review the molecular mechanisms of Gli protein regulation in mammals, with special emphasis on posttran...

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Detalhes bibliográficos
Publicado no:Cells
Main Authors: Niewiadomski, Paweł, Niedziółka, Sylwia M., Markiewicz, Łukasz, Uśpieński, Tomasz, Baran, Brygida, Chojnowska, Katarzyna
Formato: Artigo
Idioma:Inglês
Publicado em: MDPI 2019
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6406693/
https://ncbi.nlm.nih.gov/pubmed/30754706
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3390/cells8020147
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