FBXW7 in Cancer: What Has Been Unraveled Thus Far?

The FBXW7 (F-box with 7 tandem WD40) protein encoded by the gene FBXW7 is one of the crucial components of ubiquitin ligase called Skp1-Cullin1-F-box (SCF) complex that aids in the degradation of many oncoproteins via the ubiquitin-proteasome system (UPS) thus regulating cellular growth. FBXW7 is co...

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Bibliografische gegevens
Gepubliceerd in:Cancers (Basel)
Hoofdauteurs: Sailo, Bethsebie Lalduhsaki, Banik, Kishore, Girisa, Sosmitha, Bordoloi, Devivasha, Fan, Lu, Halim, Clarissa Esmeralda, Wang, Hong, Kumar, Alan Prem, Zheng, Dali, Mao, Xinliang, Sethi, Gautam, Kunnumakkara, Ajaikumar Bahulayan
Formaat: Artigo
Taal:Inglês
Gepubliceerd in: MDPI 2019
Onderwerpen:
Review
Online toegang:https://ncbi.nlm.nih.gov/pmc/articles/PMC6406609/
https://ncbi.nlm.nih.gov/pubmed/30791487
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3390/cancers11020246
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