The PERK Branch of the Unfolded Protein Response Promotes DLL4 Expression by Activating an Alternative Translation Mechanism

Delta-like 4 (DLL4) is a pivotal endothelium specific Notch ligand that has been shown to function as a regulating factor during physiological and pathological angiogenesis. DLL4 functions as a negative regulator of angiogenic branching and sprouting. Interestingly, Dll4 is with Vegf-a one of the fe...

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Bibliographic Details
Published in:Cancers (Basel)
Main Authors: Jaud, Manon, Philippe, Céline, Van Den Berghe, Loic, Ségura, Christèle, Mazzolini, Laurent, Pyronnet, Stéphane, Laurell, Henrik, Touriol, Christian
Format: Artigo
Language:Inglês
Published: MDPI 2019
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Article
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC6406545/
https://ncbi.nlm.nih.gov/pubmed/30691003
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3390/cancers11020142
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