Impairment of Motor Function Correlates with Neurometabolite and Brain Iron Alterations in Parkinson’s Disease

We took advantage of magnetic resonance imaging (MRI) and spectroscopy (MRS) as non-invasive methods to quantify brain iron and neurometabolites, which were analyzed along with other predictors of motor dysfunction in Parkinson’s disease (PD). Tapping hits, tremor amplitude, and the scores derived f...

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Udgivet i:Cells
Main Authors: Pesch, Beate, Casjens, Swaantje, Woitalla, Dirk, Dharmadhikari, Shalmali, Edmondson, David A., Zella, Maria Angela Samis, Lehnert, Martin, Lotz, Anne, Herrmann, Lennard, Muhlack, Siegfried, Kraus, Peter, Yeh, Chien-Lin, Glaubitz, Benjamin, Schmidt-Wilcke, Tobias, Gold, Ralf, van Thriel, Christoph, Brüning, Thomas, Tönges, Lars, Dydak, Ulrike
Format: Artigo
Sprog:Inglês
Udgivet: MDPI 2019
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Article
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC6406520/
https://ncbi.nlm.nih.gov/pubmed/30699914
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3390/cells8020096
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