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Novel Immunotherapeutic Approaches to Target Alpha-Synuclein and Related Neuroinflammation in Parkinson’s Disease

The etiology of Parkinson’s disease (PD) is significantly influenced by disease-causing changes in the protein alpha-Synuclein (aSyn). It can trigger and promote intracellular stress and thereby impair the function of dopaminergic neurons. However, these damage mechanisms do not only extend to neuro...

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Pubblicato in:Cells
Autori principali: Zella, Maria Angela Samis, Metzdorf, Judith, Ostendorf, Friederike, Maass, Fabian, Muhlack, Siegfried, Gold, Ralf, Haghikia, Aiden, Tönges, Lars
Natura: Artigo
Lingua:Inglês
Pubblicazione: MDPI 2019
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Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC6406239/
https://ncbi.nlm.nih.gov/pubmed/30708997
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3390/cells8020105
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