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Secondary structure of the segment 5 genomic RNA of influenza A virus and its application for designing antisense oligonucleotides

Influenza virus causes seasonal epidemics and dangerous pandemic outbreaks. It is a single stranded (−)RNA virus with a segmented genome. Eight segments of genomic viral RNA (vRNA) form the virion, which are then transcribed and replicated in host cells. The secondary structure of vRNA is an importa...

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Bibliographische Detailangaben
Veröffentlicht in:Sci Rep
Hauptverfasser: Michalak, Paula, Soszynska-Jozwiak, Marta, Biala, Ewa, Moss, Walter N., Kesy, Julita, Szutkowska, Barbara, Lenartowicz, Elzbieta, Kierzek, Ryszard, Kierzek, Elzbieta
Format: Artigo
Sprache:Inglês
Veröffentlicht: Nature Publishing Group UK 2019
Schlagworte:
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC6406010/
https://ncbi.nlm.nih.gov/pubmed/30846846
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41598-019-40443-7
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