Responsive Cells for rhEGF bioassay Obtained through Screening of a CRISPR/Cas9 Library

Bioassay of recombinant protein products is important tests to ensure protein effectiveness. Some recombinant protein products have no cells used in their bioassay but instead use animal models, while others have no suitable method. Here, we developed a method to obtain responsive cells used in bioa...

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Vydáno v:Sci Rep
Hlavní autoři: Qin, Xi, Yao, Wenrong, Shi, Xinchang, Liu, Lan, Huang, Fang, Ding, Youxue, Zhou, Yong, Yu, Lei, Jia, Chuncui, Li, Shanhu, Rao, Chunming, Wang, Junzhi
Médium: Artigo
Jazyk:Inglês
Vydáno: Nature Publishing Group UK 2019
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On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC6405917/
https://ncbi.nlm.nih.gov/pubmed/30846752
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41598-019-40381-4
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