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Targeting EGFR exon 20 insertion mutations in non-small cell lung cancer

Inframe insertions of three or more base pairs in exon 20 of the epidermal growth factor receptor (EGFR) gene were among the first EGFR mutations to be identified as oncogenic drivers in non-small cell lung cancer (NSCLC). However, unlike the classical EGFR L858R point mutation or exon 19 deletions,...

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Bibliografiska uppgifter
I publikationen:Signal Transduct Target Ther
Huvudupphovsmän: Vyse, Simon, Huang, Paul H.
Materialtyp: Artigo
Språk:Inglês
Publicerad: Nature Publishing Group UK 2019
Ämnen:
Länkar:https://ncbi.nlm.nih.gov/pmc/articles/PMC6405763/
https://ncbi.nlm.nih.gov/pubmed/30854234
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41392-019-0038-9
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