Early Onset Preeclampsia Is Associated With Glycocalyx Degradation and Reduced Microvascular Perfusion

BACKGROUND: The endothelial glycocalyx is a vasoprotective barrier between the blood and endothelium. We hypothesized that glycocalyx degradation is present in preeclampsia, a pregnancy‐specific hypertensive disorder characterized by endothelial dysfunction and activation. METHODS AND RESULTS: We ex...

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Detalhes bibliográficos
Publicado no:J Am Heart Assoc
Main Authors: Weissgerber, Tracey L., Garcia‐Valencia, Oscar, Milic, Natasa M., Codsi, Elizabeth, Cubro, Hajrunisa, Nath, Meryl C., White, Wendy M., Nath, Karl A., Garovic, Vesna D.
Formato: Artigo
Idioma:Inglês
Publicado em: John Wiley and Sons Inc. 2019
Assuntos:
Original Research
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6405679/
https://ncbi.nlm.nih.gov/pubmed/30764695
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1161/JAHA.118.010647
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