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Genetic predisposition to MDS: clinical features and clonal evolution

Myelodysplastic syndrome (MDS) typically presents in older adults with the acquisition of age-related somatic mutations, whereas MDS presenting in children and younger adults is more frequently associated with germline genetic predisposition. Germline predisposition is increasingly recognized in MDS...

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Pubblicato in:Blood
Autori principali: Kennedy, Alyssa L., Shimamura, Akiko
Natura: Artigo
Lingua:Inglês
Pubblicazione: American Society of Hematology 2019
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Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC6405331/
https://ncbi.nlm.nih.gov/pubmed/30670445
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1182/blood-2018-10-844662
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