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The Design and Analysis of Seroefficacy Studies for Typhoid Conjugate Vaccines

BACKGROUND: Demonstrating the efficacy of new Vi-conjugate typhoid vaccines is challenging, due to the cost of field trials requiring tens of thousands of participants. New trial designs that use serologically defined typhoid infections (seroefficacy trials) rather than blood culture positivity as a...

Disgrifiad llawn

Wedi'i Gadw mewn:
Manylion Llyfryddiaeth
Cyhoeddwyd yn:Clin Infect Dis
Prif Awduron: Liu, Xinxue, Pitzer, Virginia E, Pollard, Andrew J, Voysey, Merryn
Fformat: Artigo
Iaith:Inglês
Cyhoeddwyd: Oxford University Press 2019
Pynciau:
Mynediad Ar-lein:https://ncbi.nlm.nih.gov/pmc/articles/PMC6405265/
https://ncbi.nlm.nih.gov/pubmed/30845326
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/cid/ciy1119
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