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Nanobody immunostaining for correlated light and electron microscopy with preservation of ultrastructure

Morphological and molecular characteristics determine the function of biological tissues. Attempts to combine immunofluorescence and electron microscopy invariably compromise the quality of the ultrastructure of tissue sections. We developed NATIVE, a correlated light and electron microscopy approac...

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Détails bibliographiques
Publié dans:Nat Methods
Auteurs principaux: Fang, Tao, Lu, Xiaotang, Berger, Daniel, Gmeiner, Christina, Cho, Julia, Schalek, Richard, Ploegh, Hidde, Lichtman, Jeff
Format: Artigo
Langue:Inglês
Publié: 2018
Sujets:
Accès en ligne:https://ncbi.nlm.nih.gov/pmc/articles/PMC6405223/
https://ncbi.nlm.nih.gov/pubmed/30397326
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41592-018-0177-x
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