Adolescent idiopathic scoliosis associated POC5 mutation impairs cell cycle, cilia length and centrosome protein interactions

Adolescent Idiopathic Scoliosis (AIS) is a spinal deformity that affects approximately 3 percent of human adolescents. Although the etiology and molecular basis of AIS is unclear, several genes such as POC5 have been identified as possible causes of the condition. In order to understand the role of...

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Veröffentlicht in:PLoS One
Hauptverfasser: Hassan, Amani, Parent, Stefan, Mathieu, Hélène, Zaouter, Charlotte, Molidperee, Sirinart, Bagu, Edward T., Barchi, Soraya, Villemure, Isabelle, Patten, Shunmoogum A., Moldovan, Florina
Format: Artigo
Sprache:Inglês
Veröffentlicht: Public Library of Science 2019
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Research Article
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC6405090/
https://ncbi.nlm.nih.gov/pubmed/30845169
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0213269
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