Novel behavioral signs of spontaneous and precipitated THC withdrawal in mice

BACKGROUND: A subset of cannabis users develop some degree of Cannabis Use Disorder (CUD). Although behavioral therapy has some success in treating CUD, many users relapse, often citing altered sleep, mood, and irritability. Preclinical animal models of cannabinoid withdrawal focus primarily on soma...

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Опубликовано в: :Drug Alcohol Depend
Главные авторы: Trexler, Kristen R., Nass, Sara R., Crowe, Molly S., Gross, Joshua D., Jones, Margaret S., McKitrick, Austin W., Siderovski, David P., Kinsey, Steven G.
Формат: Artigo
Язык:Inglês
Опубликовано: 2018
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Article
Online-ссылка:https://ncbi.nlm.nih.gov/pmc/articles/PMC6404969/
https://ncbi.nlm.nih.gov/pubmed/30071445
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.drugalcdep.2018.05.029
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