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Disparate Remodeling of the Extracellular Matrix and Proteoglycans in Failing Pediatric Versus Adult Hearts

BACKGROUND: Dilated cardiomyopathy (DCM) is a common cause of heart failure in adult and pediatric patients, but the underlying mechanism may vary in adults and children, with few studies conducted to date. The objective of the present study was to determine whether differential remodeling of the ex...

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Pubblicato in:J Am Heart Assoc
Autori principali: Jana, Sayantan, Zhang, Hao, Lopaschuk, Gary D., Freed, Darren H., Sergi, Consolato, Kantor, Paul F., Oudit, Gavin Y., Kassiri, Zamaneh
Natura: Artigo
Lingua:Inglês
Pubblicazione: John Wiley and Sons Inc. 2018
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Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC6404896/
https://ncbi.nlm.nih.gov/pubmed/30371322
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1161/JAHA.118.010427
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