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2-Methoxyestradiol Attenuates Angiotensin II-Induced Hypertension, Cardiovascular Remodeling and Renal Injury

Estradiol may antagonize the adverse cardiovascular effects of angiotensin II (Ang II). We investigated the effects 2-methoxyestradiol (2-ME), a non-estrogenic estradiol metabolite, on Ang II-induced cardiovascular and renal injury in male rats. First, we determined the effects of 2ME on Ang II-indu...

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Bibliografiska uppgifter
I publikationen:J Cardiovasc Pharmacol
Huvudupphovsmän: Salah, Eman, Bastacky, Sheldon I., Jackson, Edwin K., Tofovic, Stevan P.
Materialtyp: Artigo
Språk:Inglês
Publicerad: 2019
Ämnen:
Länkar:https://ncbi.nlm.nih.gov/pmc/articles/PMC6404767/
https://ncbi.nlm.nih.gov/pubmed/30839510
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1097/FJC.0000000000000649
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