Preparation, intestinal segment stability, and mucoadhesion properties of novel thymopentin-loaded chitosan derivatives coated with poly (n-butyl) cyanoacrylate nanoparticles

BACKGROUND: In order to develop a promising carrier for the oral delivery of proteins and peptide drugs, a novel bioadhesive nanocarrier of chitosan (CTS) derivatives coated with poly (n-butyl) cyanoacrylate nanoparticles (PBCA-NPs) was prepared in this study. METHODS: Three different thymopentin (T...

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Detalhes bibliográficos
Publicado no:Int J Nanomedicine
Main Authors: Xu, Ying, Lu, Shengzhe, Liu, Qi, Hong, Yun, Xu, Bohui, Ping, Qineng, Jin, Xuefeng, Shen, Yan, Webster, Thomas J, Rao, Yuefeng
Formato: Artigo
Idioma:Inglês
Publicado em: Dove Medical Press 2019
Assuntos:
Original Research
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6404670/
https://ncbi.nlm.nih.gov/pubmed/30880971
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.2147/IJN.S194529
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