High Prevalence of Abacavir-associated L74V/I Mutations in Kenyan Children Failing Antiretroviral Therapy

A survey of 461 HIV-infected Kenyan children receiving antiretroviral therapy found 143 (31%) failing virologically. Drug resistance mutations were found in 121; 37 had L74V/I mutations, with 95% receiving abacavir (ABC)-containing regimens. L74V/I was associated with current ABC usage (P = 0.0001)....

ver descrição completa

Na minha lista:
Detalhes bibliográficos
Publicado no:Pediatr Infect Dis J
Main Authors: Dziuban, Eric J., DeVos, Joshua, Ngeno, Bernadette, Ngugi, Evelyn, Zhang, Guoqing, Sabatier, Jennifer, Wagar, Nick, Diallo, Karidia, Nganga, Lucy, Katana, Abraham, Yang, Chunfu, Rivadeneira, Emilia D., Mukui, Irene, Odhiambo, Francesca, Redfield, Robert, Raizes, Elliot
Formato: Artigo
Idioma:Inglês
Publicado em: 2017
Assuntos:
Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6404536/
https://ncbi.nlm.nih.gov/pubmed/28383390
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1097/INF.0000000000001597
Tags: Adicionar Tag
Sem tags, seja o primeiro a adicionar uma tag!

Registos relacionados