Coronary heart disease mortality in severe vs. non-severe familial hypercholesterolaemia in the Simon Broome Register

BACKGROUND AND AIMS: The International Atherosclerosis Society (IAS) has proposed that patients with “severe” FH (SFH) would warrant early and more aggressive cholesterol-lowering treatment such as with PCSK9 inhibitors. SFH is diagnosed if LDL-cholesterol (LDLC) > 10 mmol/L, or LDLC >8.0 mmol...

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Vydáno v:Atherosclerosis
Hlavní autoři: Humphries, Steve E., Cooper, Jackie A., Capps, Nigel, Durrington, Paul N., Jones, Ben, McDowell, Ian F.W., Soran, Handrean, Neil, Andrew H.W.
Médium: Artigo
Jazyk:Inglês
Vydáno: Elsevier 2019
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Article
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC6403443/
https://ncbi.nlm.nih.gov/pubmed/30458964
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.atherosclerosis.2018.11.014
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