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Long term seizure freedom on perampanel in highly drug-resistant epilepsy caused by bilateral periventricular nodular heterotopia: A case report

• NMDA-receptor subunit expression of NR2A and NR2B is downregulated in heterotopias. • Glutamatergic transmission in the hyperexcitability of nodular heterotopias is implicated. • Mechanisms in PVNH to establish etiology specific therapies are still to be defined.

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Podrobná bibliografie
Vydáno v:Epilepsy Behav Case Rep
Hlavní autoři: Kiyose, Makoto, Wagner, Marlies, Männer, Annika, Reitz, Sarah C., Klein, Karl Martin, Strzelczyk, Adam, Bauer, Sebastian, Rosenow, Felix
Médium: Artigo
Jazyk:Inglês
Vydáno: Elsevier 2019
Témata:
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC6403409/
https://ncbi.nlm.nih.gov/pubmed/30891403
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.ebcr.2019.01.009
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