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TGR5 activation ameliorates hyperglycemia-induced cardiac hypertrophy in H9c2 cells

Left ventricular hypertrophy is an independent risk factor in diabetic patients. TGR5 is shown to express in hearts, but its functional role in diabetes-induced cardiac hypertrophy remained unclear. The current study investigated the role of TGR5 on high glucose-induced hypertrophy of H9C2 cells. Af...

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Détails bibliographiques
Publié dans:Sci Rep
Auteurs principaux: Cheng, Kai-Chun, Chang, Wei-Ting, Kuo, Feng Yu, Chen, Zhih-Cherng, Li, Yingxiao, Cheng, Juei-Tang
Format: Artigo
Langue:Inglês
Publié: Nature Publishing Group UK 2019
Sujets:
Accès en ligne:https://ncbi.nlm.nih.gov/pmc/articles/PMC6403401/
https://ncbi.nlm.nih.gov/pubmed/30842472
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41598-019-40002-0
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