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Prevention of EloR/KhpA heterodimerization by introduction of site-specific amino acid substitutions renders the essential elongasome protein PBP2b redundant in Streptococcus pneumoniae

The RNA binding proteins EloR and KhpA are important components of the regulatory network that controls and coordinates cell elongation and division in S. pneumoniae. Loss of either protein reduces cell length, and makes the essential elongasome proteins PBP2b and RodA dispensable. It has been shown...

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Detalhes bibliográficos
Publicado no:Sci Rep
Main Authors: Winther, Anja Ruud, Kjos, Morten, Stamsås, Gro Anita, Håvarstein, Leiv Sigve, Straume, Daniel
Formato: Artigo
Idioma:Inglês
Publicado em: Nature Publishing Group UK 2019
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Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6403258/
https://ncbi.nlm.nih.gov/pubmed/30842445
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41598-018-38386-6
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