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Proteomic changes in oocytes after in vitro maturation in lipotoxic conditions are different from those in cumulus cells
Maternal lipolytic metabolic disorders result in a lipotoxic microenvironment in the ovarian follicular fluid (FF) which deteriorates oocyte quality. Although cellular stress response mechanisms are well defined in somatic cells, they remain largely unexplored in oocytes, which have distinct organel...
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| 出版年: | Sci Rep |
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| 主要な著者: | , , , , |
| フォーマット: | Artigo |
| 言語: | Inglês |
| 出版事項: |
Nature Publishing Group UK
2019
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| 主題: | |
| オンライン･アクセス: | https://ncbi.nlm.nih.gov/pmc/articles/PMC6403224/ https://ncbi.nlm.nih.gov/pubmed/30842615 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41598-019-40122-7 |
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