Aromatic Bromination Abolishes the Psychomotor Features and Pro-social Responses of MDMA (“Ecstasy”) in Rats and Preserves Affinity for the Serotonin Transporter (SERT)

The entactogen MDMA (3,4-methylenedioxy-methamphetamine, “Ecstasy”) exerts its psychotropic effects acting primarily as a substrate of the serotonin transporter (SERT) to induce a non-exocytotic release of serotonin. Nevertheless, the roles of specific positions of the aromatic ring of MDMA associat...

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Detalhes bibliográficos
Publicado no:Front Pharmacol
Main Authors: Sáez-Briones, Patricio, Castro-Castillo, Vicente, Díaz-Véliz, Gabriela, Valladares, Luis, Barra, Rafael, Hernández, Alejandro, Cassels, Bruce K.
Formato: Artigo
Idioma:Inglês
Publicado em: Frontiers Media S.A. 2019
Assuntos:
Pharmacology
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6403168/
https://ncbi.nlm.nih.gov/pubmed/30873030
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3389/fphar.2019.00157
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