Ex vivo-expanded highly purified natural killer cells in combination with temozolomide induce antitumor effects in human glioblastoma cells in vitro

Glioblastoma is the leading malignant glioma with a poor prognosis. This study aimed to investigate the antitumor effects of natural killer cells in combination with temozolomide as the standard chemotherapeutic agent for glioblastoma. Using a simple, feeder-less, and chemically defined culture meth...

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Udgivet i:PLoS One
Main Authors: Tanaka, Yoshitaka, Nakazawa, Tsutomu, Nakamura, Mitsutoshi, Nishimura, Fumihiko, Matsuda, Ryosuke, Omoto, Koji, Shida, Yoichi, Murakami, Toshiharu, Nakagawa, Ichiro, Motoyama, Yasushi, Morita, Hiromichi, Tsujimura, Takahiro, Nakase, Hiroyuki
Format: Artigo
Sprog:Inglês
Udgivet: Public Library of Science 2019
Fag:
Research Article
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC6402639/
https://ncbi.nlm.nih.gov/pubmed/30840664
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0212455
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