Ubenimex Reverses MDR in Gastric Cancer Cells by Activating Caspase-3-Mediated Apoptosis and Suppressing the Expression of Membrane Transport Proteins

Gastric cancer (GC) is one of the most malignant tumors, accounting for 10% of deaths caused by all cancers. Chemotherapy is often necessary for treatment of GC; the FOLFOX regimen is extensively applied. However, multidrug resistance (MDR) of GC cells prevents wider application of this treatment. U...

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Udgivet i:Biomed Res Int
Main Authors: Guo, Qie, Jing, Fan-jing, Qu, Hai-jun, Xu, Wen, Han, Bing, Xing, Xiao-min, Ji, Hong-yan, Jing, Fan-Bo
Format: Artigo
Sprog:Inglês
Udgivet: Hindawi 2019
Fag:
Research Article
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC6402206/
https://ncbi.nlm.nih.gov/pubmed/30915355
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1155/2019/4390839
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