Upregulation of MUC5AC production and deposition of LEWIS determinants by HELICOBACTER PYLORI facilitate gastric tissue colonization and the maintenance of infection

BACKGROUND: Helicobacter pylori bacteria colonize human gastric mucosa, cause chronic inflammation, peptic ulcers and gastric cancer. Colonization is mediated by H. pylori adhesins, which preferentially bind mucin 5 (MUC5AC) and Lewis (Le) determinants. The aim of this study was to evaluate the infl...

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Wedi'i Gadw mewn:
Manylion Llyfryddiaeth
Cyhoeddwyd yn:J Biomed Sci
Prif Awduron: Gonciarz, Weronika, Walencka, Maria, Moran, Anthony P., Hinc, Krzysztof, Obuchowski, Michał, Chmiela, Magdalena
Fformat: Artigo
Iaith:Inglês
Cyhoeddwyd: BioMed Central 2019
Pynciau:
Research
Mynediad Ar-lein:https://ncbi.nlm.nih.gov/pmc/articles/PMC6402143/
https://ncbi.nlm.nih.gov/pubmed/30841890
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/s12929-019-0515-z
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