Silencing of lncRNA PKIA-AS1 Attenuates Spinal Nerve Ligation-Induced Neuropathic Pain Through Epigenetic Downregulation of CDK6 Expression

Neuropathic pain (NP) is among the most intractable comorbidities of spinal cord injury. Dysregulation of non-coding RNAs has also been implicated in the development of neuropathic pain. Here, we identified a novel lncRNA, PKIA-AS1, by using lncRNA array analysis in spinal cord tissue of spinal nerv...

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Detalhes bibliográficos
Publicado no:Front Cell Neurosci
Main Authors: Hu, Jian-Zhong, Rong, Zi-Jie, Li, Miao, Li, Ping, Jiang, Li-Yuan, Luo, Zi-Xiang, Duan, Chun-Yue, Cao, Yong, Lu, Hong-Bin
Formato: Artigo
Idioma:Inglês
Publicado em: Frontiers Media S.A. 2019
Assuntos:
Neuroscience
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6401634/
https://ncbi.nlm.nih.gov/pubmed/30873006
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3389/fncel.2019.00050
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