A DNase from a Fungal Phytopathogen Is a Virulence Factor Likely Deployed as Counter Defense against Host-Secreted Extracellular DNA

Histone-linked extracellular DNA (exDNA) is a component of neutrophil extracellular traps (NETs). NETs have been shown to play a role in immune response to bacteria, fungi, viruses, and protozoan parasites. Mutation of genes encoding group A Streptococcus extracellular DNases (exDNases) results in r...

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Pubblicato in:mBio
Autori principali: Park, Hee-Jin, Wang, Weiwei, Curlango-Rivera, Gilberto, Xiong, Zhongguo, Lin, Zeran, Huskey, David A., Hawes, Martha C., VanEtten, Hans D., Turgeon, B. Gillian
Natura: Artigo
Lingua:Inglês
Pubblicazione: American Society for Microbiology 2019
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Research Article
Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC6401486/
https://ncbi.nlm.nih.gov/pubmed/30837342
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/mBio.02805-18
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