West Nile Virus-Inclusive Single-Cell RNA Sequencing Reveals Heterogeneity in the Type I Interferon Response within Single Cells

West Nile virus (WNV) is a neurotropic mosquito-borne flavivirus of global importance. Neuroinvasive WNV infection results in encephalitis and can lead to prolonged neurological impairment or death. Type I interferon (IFN-I) is crucial for promoting antiviral defenses through the induction of antivi...

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Détails bibliographiques
Publié dans:J Virol
Auteurs principaux: O’Neal, Justin T., Upadhyay, Amit A., Wolabaugh, Amber, Patel, Nirav B., Bosinger, Steven E., Suthar, Mehul S.
Format: Artigo
Langue:Inglês
Publié: American Society for Microbiology 2019
Sujets:
Cellular Response to Infection
Accès en ligne:https://ncbi.nlm.nih.gov/pmc/articles/PMC6401468/
https://ncbi.nlm.nih.gov/pubmed/30626670
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/JVI.01778-18
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