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Glycoprotein K8.1A of Kaposi's Sarcoma-Associated Herpesvirus Is a Critical B Cell Tropism Determinant Independent of Its Heparan Sulfate Binding Activity

B lymphocytes are the major cellular reservoir in individuals infected with Kaposi’s sarcoma-associated herpesvirus (KSHV), and the virus is etiologically linked to two B cell lymphoproliferative disorders. We previously described the MC116 human B cell line as a KSHV-susceptible model to overcome t...

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Detalhes bibliográficos
Publicado no:J Virol
Main Authors: Dollery, Stephen J., Santiago-Crespo, Rey J., Chatterjee, Deboeeta, Berger, Edward A.
Formato: Artigo
Idioma:Inglês
Publicado em: American Society for Microbiology 2019
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6401448/
https://ncbi.nlm.nih.gov/pubmed/30567992
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/JVI.01876-18
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