Unique Transcriptional Architecture in Airway Epithelial Cells and Macrophages Shapes Distinct Responses following Influenza Virus Infection Ex Vivo

Airway epithelial cells and macrophages differ markedly in their responses to influenza A virus (IAV) infection. To investigate transcriptional responses underlying these differences, purified subsets of type II airway epithelial cells (ATII) and alveolar macrophages (AM) recovered from the lungs of...

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Veröffentlicht in:J Virol
Hauptverfasser: Ma, Joel Z., Ng, Wy Ching, Zappia, Luke, Gearing, Linden J., Olshansky, Moshe, Pham, Kym, Cheong, Karey, Hsu, Arthur, Turner, Stephen J., Wijburg, Odilia, Londrigan, Sarah L., Brooks, Andrew G., Reading, Patrick C.
Format: Artigo
Sprache:Inglês
Veröffentlicht: American Society for Microbiology 2019
Schlagworte:
Cellular Response to Infection
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC6401432/
https://ncbi.nlm.nih.gov/pubmed/30626665
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/JVI.01986-18
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