GSH-sensitive Pt(IV) prodrug-loaded phase-transitional nanoparticles with a hybrid lipid-polymer shell for precise theranostics against ovarian cancer

Background: Platinum (II) (Pt(II))-based anticancer drugs dominate the chemotherapy field of ovarian cancer. However, the patient's quality of life has severely limited owing to dose-limiting toxicities and the advanced disease at the time of diagnosis. Multifunctional tumor-targeted nanosized...

Disgrifiad llawn

Wedi'i Gadw mewn:
Manylion Llyfryddiaeth
Cyhoeddwyd yn:Theranostics
Prif Awduron: Huang, Hui, Dong, Yang, Zhang, Yanhua, Ru, Dan, Wu, Zhihua, Zhang, Jiali, Shen, Ming, Duan, Yourong, Sun, Ying
Fformat: Artigo
Iaith:Inglês
Cyhoeddwyd: Ivyspring International Publisher 2019
Pynciau:
Research Paper
Mynediad Ar-lein:https://ncbi.nlm.nih.gov/pmc/articles/PMC6401401/
https://ncbi.nlm.nih.gov/pubmed/30867815
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.7150/thno.29820
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