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Cytohesin-3 is required for full insulin receptor signaling and controls body weight via lipid excretion

Insulin plays a central role in regulating metabolic homeostasis and guanine-nucleotide exchange factors of the cytohesin family have been suggested to be involved in insulin signal transduction. The Drosophila homolog of cytohesin-3, steppke, has been shown to be essential for insulin signaling dur...

Ausführliche Beschreibung

Gespeichert in:
Bibliographische Detailangaben
Veröffentlicht in:Sci Rep
Hauptverfasser: Jux, Bettina, Gosejacob, Dominic, Tolksdorf, Felix, Mandel, Christa, Rieck, Michael, Namislo, Angrit, Pfeifer, Alexander, Kolanus, Waldemar
Format: Artigo
Sprache:Inglês
Veröffentlicht: Nature Publishing Group UK 2019
Schlagworte:
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC6401384/
https://ncbi.nlm.nih.gov/pubmed/30837656
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41598-019-40231-3
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