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A longitudinal model of human neuronal differentiation for functional investigation of schizophrenia polygenic risk

BACKGROUND: Common psychiatric disorders are characterized by complex disease architectures with many small genetic effects that contribute and complicate biological understanding of their etiology. There is therefore a pressing need for in vitro experimental systems that allow for interrogation of...

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Publicat a:Biol Psychiatry
Autors principals: Ori, Anil P.S., Bot, Merel H.M., Molenhuis, Remco T., Olde Loohuis, Loes M., Ophoff, Roel A.
Format: Artigo
Idioma:Inglês
Publicat: 2018
Matèries:
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC6401362/
https://ncbi.nlm.nih.gov/pubmed/30340753
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.biopsych.2018.08.019
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