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Protein Aggregation linked to Alzheimer’s Disease Revealed by Saturation Transfer MRI

The goal of this study was to develop a molecular biomarker for the detection of protein aggregation involved in Alzheimer’s disease (AD) by exploiting the features of the water saturation transfer spectrum (Z-spectrum), the CEST signal of which is sensitive to the molecular configuration of protein...

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Detalhes bibliográficos
Publicado no:Neuroimage
Main Authors: Chen, Lin, Wei, Zhiliang, Chan, Kannie, Cai, Shuhui, Liu, Guanshu, Lu, Hanzhang, Wong, Philip C., van Zijl, Peter C. M., Li, Tong, Xu, Jiadi
Formato: Artigo
Idioma:Inglês
Publicado em: 2018
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Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6401270/
https://ncbi.nlm.nih.gov/pubmed/30553917
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.neuroimage.2018.12.018
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