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IL-10 and ICOS differentially regulate T cell responses in the brain during chronic Toxoplasma gondii infection

Control of chronic CNS infection with the parasite Toxoplasma gondii requires ongoing T cell responses in the brain. Immunosuppressive cytokines are also important for preventing lethal immunopathology during chronic infection. To explore the loss of suppressive cytokine exclusively during the chron...

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Détails bibliographiques
Publié dans:J Immunol
Auteurs principaux: O’Brien, Carleigh A., Batista, Samantha J., Still, Katherine M., Harris, Tajie H.
Format: Artigo
Langue:Inglês
Publié: 2019
Sujets:
Accès en ligne:https://ncbi.nlm.nih.gov/pmc/articles/PMC6401250/
https://ncbi.nlm.nih.gov/pubmed/30718297
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.4049/jimmunol.1801229
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