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Highly-branched poly(N-isopropyl acrylamide) functionalised with pendant Nile red and chain end vancomycin for the detection of Gram-positive bacteria

This study shows how highly branched poly(N-isopropyl acrylamide) (HB-PNIPAM) with a chain pendant solvatochromic dye (Nile red) could provide a fluorescence signal, as end groups bind to bacteria and chain segments become desolvated, indicating the presence of bacteria. Vancomycin was attached to c...

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Bibliographic Details
Published in:Acta Biomater
Main Authors: Swift, Thomas, Katsikogianni, Maria, Hoskins, Richard, Teratarantorn, Pavintorn, Douglas, Ian, MacNeil, Sheila, Rimmer, Stephen
Format: Artigo
Language:Inglês
Published: Elsevier 2019
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Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC6401204/
https://ncbi.nlm.nih.gov/pubmed/30711663
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.actbio.2019.01.066
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