The genetic vulnerability to cisplatin ototoxicity: a systematic review

Ototoxicity is one of the major side-effects of platinum-based chemotherapy, in particular cisplatin (cis-diammine dichloroplatinum II). To our knowledge, no systematic review has previously provided a quantitative summary estimate of the impact of genetics upon the risk of developing hearing loss....

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Udgivet i:Sci Rep
Main Authors: Tserga, Evangelia, Nandwani, Tara, Edvall, Niklas K., Bulla, Jan, Patel, Poulam, Canlon, Barbara, Cederroth, Christopher R., Baguley, David M.
Format: Artigo
Sprog:Inglês
Udgivet: Nature Publishing Group UK 2019
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Article
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC6401165/
https://ncbi.nlm.nih.gov/pubmed/30837596
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41598-019-40138-z
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