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The landscape of d16HER2 splice variant expression across HER2-positive cancers

The HER2 splice variant characterized by the deletion of exon 16 and denominated as d16HER2, is associated with HER2-positive breast cancer (BC) aggressiveness, stemness, and trastuzumab susceptibility and is considered to be a “flag” of HER2 dependence. However, with the exception of quantitative r...

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Bibliografiska uppgifter
I publikationen:Sci Rep
Huvudupphovsmän: Volpi, Chiara Costanza, Pietrantonio, Filippo, Gloghini, Annunziata, Fucà, Giovanni, Giordano, Silvia, Corso, Simona, Pruneri, Giancarlo, Antista, Maria, Cremolini, Chiara, Fasano, Elena, Saggio, Serena, Faraci, Simona, Di Bartolomeo, Maria, de Braud, Filippo, Di Nicola, Massimo, Tagliabue, Elda, Pupa, Serenella Maria, Castagnoli, Lorenzo
Materialtyp: Artigo
Språk:Inglês
Publicerad: Nature Publishing Group UK 2019
Ämnen:
Länkar:https://ncbi.nlm.nih.gov/pmc/articles/PMC6401102/
https://ncbi.nlm.nih.gov/pubmed/30837627
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41598-019-40310-5
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