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Analysis of human acetylation stoichiometry defines mechanistic constraints on protein regulation

Lysine acetylation is a reversible posttranslational modification that occurs at thousands of sites on human proteins. However, the stoichiometry of acetylation remains poorly characterized, and is important for understanding acetylation-dependent mechanisms of protein regulation. Here we provide ac...

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Podrobná bibliografie
Vydáno v:Nat Commun
Hlavní autoři: Hansen, Bogi Karbech, Gupta, Rajat, Baldus, Linda, Lyon, David, Narita, Takeo, Lammers, Michael, Choudhary, Chunaram, Weinert, Brian T.
Médium: Artigo
Jazyk:Inglês
Vydáno: Nature Publishing Group UK 2019
Témata:
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC6401094/
https://ncbi.nlm.nih.gov/pubmed/30837475
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41467-019-09024-0
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