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Matrix-bound nanovesicles prevent ischemia-induced retinal ganglion cell axon degeneration and death and preserve visual function

Injury to retinal ganglion cells (RGC), central nervous system neurons that relay visual information to the brain, often leads to RGC axon degeneration and permanently lost visual function. Herein this study shows matrix-bound nanovesicles (MBV), a distinct class of extracellular nanovesicle localiz...

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Bibliografske podrobnosti
izdano v:Sci Rep
Main Authors: van der Merwe, Yolandi, Faust, Anne E., Sakalli, Ecem T., Westrick, Caroline C., Hussey, George, Chan, Kevin C., Conner, Ian P., Fu, Valeria L. N., Badylak, Stephen F., Steketee, Michael B.
Format: Artigo
Jezik:Inglês
Izdano: Nature Publishing Group UK 2019
Teme:
Online dostop:https://ncbi.nlm.nih.gov/pmc/articles/PMC6400956/
https://ncbi.nlm.nih.gov/pubmed/30837658
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41598-019-39861-4
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