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Emerging Therapeutic Approaches for Cystic Fibrosis. From Gene Editing to Personalized Medicine

An improved understanding of the cystic fibrosis (CF) transmembrane conductance regulator (CFTR) protein structure and the consequences of CFTR gene mutations have allowed the development of novel therapies targeting specific defects underlying CF. Some strategies are mutation specific and have alre...

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Detalhes bibliográficos
Publicado no:Front Pharmacol
Main Authors: Pranke, Iwona, Golec, Anita, Hinzpeter, Alexandre, Edelman, Aleksander, Sermet-Gaudelus, Isabelle
Formato: Artigo
Idioma:Inglês
Publicado em: Frontiers Media S.A. 2019
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6400831/
https://ncbi.nlm.nih.gov/pubmed/30873022
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3389/fphar.2019.00121
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