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Development of transcription factor-based designer macrolide biosensors for metabolic engineering and synthetic biology
Macrolides are a large group of natural products that display broad and potent biological activities and are biosynthesized by type I polyketide synthases (PKSs) and associated enzymatic machinery. There is an urgent need to access macrolides and unnatural macrolide derivatives for drug discovery, d...
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| Publicado en: | ACS Synth Biol |
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| Autores principales: | , , , , |
| Formato: | Artigo |
| Lenguaje: | Inglês |
| Publicado: |
2017
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| Materias: | |
| Acceso en línea: | https://ncbi.nlm.nih.gov/pmc/articles/PMC6400638/ https://ncbi.nlm.nih.gov/pubmed/28950701 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1021/acssynbio.7b00287 |
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