Gα(s)-coupled receptor signaling and sleep regulate integrin activation of human antigen-specific T cells

Efficient T cell responses require the firm adhesion of T cells to their targets, e.g., virus-infected cells, which depends on T cell receptor (TCR)–mediated activation of β(2)-integrins. Gα(s)-coupled receptor agonists are known to have immunosuppressive effects, but their impact on TCR-mediated in...

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Detalles Bibliográficos
Publicado en:J Exp Med
Main Authors: Dimitrov, Stoyan, Lange, Tanja, Gouttefangeas, Cécile, Jensen, Anja T.R., Szczepanski, Michael, Lehnnolz, Jannik, Soekadar, Surjo, Rammensee, Hans-Georg, Born, Jan, Besedovsky, Luciana
Formato: Artigo
Idioma:Inglês
Publicado: Rockefeller University Press 2019
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Research Articles
Acceso en liña:https://ncbi.nlm.nih.gov/pmc/articles/PMC6400544/
https://ncbi.nlm.nih.gov/pubmed/30755455
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1084/jem.20181169
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