Identification of the Human Skeletal Stem Cell

Stem cell regulation and hierarchical organization of human skeletal progenitors remain largely unexplored. Here, we report the isolation of a self-renewing and multipotent human skeletal stem cell (hSSC) that generates progenitors of bone, cartilage, and stroma, but not fat. Self-renewing and multi...

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Pubblicato in:Cell
Autori principali: Chan, Charles K. F., Gulati, Gunsagar S., Sinha, Rahul, Tompkins, Justin Vincent, Lopez, Michael, Carter, Ava C., Ransom, Ryan C., Reinisch, Andreas, Wearda, Taylor, Murphy, Matthew, Brewer, Rachel E., Koepke, Lauren S., Marecic, Owen, Manjunath, Anoop, Seo, Eun Young, Leavitt, Tripp, Lu, Wan-Jin, Nguyen, Allison, Conley, Stephanie D., Salhotra, Ankit, Ambrosi, Thomas H., Borrelli, Mimi R., Siebel, Taylor, Chan, Karen, Schallmoser, Katharina, Seita, Jun, Sahoo, Debashis, Goodnough, Henry, Bishop, Julius, Gardner, Michael, Majeti, Ravindra, Wan, Derrick C., Goodman, Stuart, Weissman, Irving L., Chang, Howard Y., Longaker, Michael T.
Natura: Artigo
Lingua:Inglês
Pubblicazione: 2018
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Article
Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC6400492/
https://ncbi.nlm.nih.gov/pubmed/30241615
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.cell.2018.07.029
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